Symptoms of pain will be experienced someone who is infected with rabies includes 4 stages:
Prodromal stage
In stage prodomal pain arising in patients with atypical, resemble viral infections in general, which include fever, difficult to eat that led extent anorexia, headache and dizziness (nausea), and so forth.
Sensory Stadium
In the sensory stage patients will generally experience pain in the bite area, heat, nervousness, confusion, came out a lot of saliva (hypersalivation), dilated pupils, hyperhidrosis, hiperlakrimasi.
Stadium excitation
At the excitation stage patients become restless, easily startled, convulsions every stimulus from the outside, causing fear in the air (aerofobia), fear of light (photophobia), and fear of water (hidrofobia). Convulsions due to the disruption of the brain areas that regulate the process of swallowing and breathing. Hidrofobia that occur in people with rabies, especially because of the incredible pain at the time tried to swallow water
Paralytic stage
In the paralytic stage after going through three stages before entering the stadium paralytic patient shows signs of paralysis of the upper body down progressive.
Because the duration of the disease spreading fast enough then the fourth stage above generally can not be distinguished clearly. The symptoms that was evident in patients in whom the pain at the bite wound and the fear of water, air and light, and a loud voice. While on an infected animal, which looks gelaja is from benign to malignant, pets go wild and forget the way back, and tail curved under the belly.
Diagnosis
If someone is bitten by animals, then animals that bite must be supervised. The only test that produced 100% accuracy for the presence of rabies virus is by direct fluorescent antibody test (direct fluorescent antibody test / DFAT) in brain tissue of infected animals. This test has been used for more than 40 years and used as a standard in the diagnosis of rabies. The principle is that the bond between rabies antigen and specific antibodies that have been labeled with a fluorescent compound that will glow making it easier detection. However, the drawback is the test subject must be injected prior to death (euthanasia) can therefore not be used on humans. However, similar tests can still be done using serum, spinal fluid, or saliva of patients while not giving 100% accuracy. In addition, the diagnosis can also be done with the neck skin biopsy or corneal epithelial cells, although the results are not very precise so that will be done again after the post mortem diagnosis of infected animals or humans died.
Prodromal stage
In stage prodomal pain arising in patients with atypical, resemble viral infections in general, which include fever, difficult to eat that led extent anorexia, headache and dizziness (nausea), and so forth.
Sensory Stadium
In the sensory stage patients will generally experience pain in the bite area, heat, nervousness, confusion, came out a lot of saliva (hypersalivation), dilated pupils, hyperhidrosis, hiperlakrimasi.
Stadium excitation
At the excitation stage patients become restless, easily startled, convulsions every stimulus from the outside, causing fear in the air (aerofobia), fear of light (photophobia), and fear of water (hidrofobia). Convulsions due to the disruption of the brain areas that regulate the process of swallowing and breathing. Hidrofobia that occur in people with rabies, especially because of the incredible pain at the time tried to swallow water
Paralytic stage
In the paralytic stage after going through three stages before entering the stadium paralytic patient shows signs of paralysis of the upper body down progressive.
Because the duration of the disease spreading fast enough then the fourth stage above generally can not be distinguished clearly. The symptoms that was evident in patients in whom the pain at the bite wound and the fear of water, air and light, and a loud voice. While on an infected animal, which looks gelaja is from benign to malignant, pets go wild and forget the way back, and tail curved under the belly.
Diagnosis
If someone is bitten by animals, then animals that bite must be supervised. The only test that produced 100% accuracy for the presence of rabies virus is by direct fluorescent antibody test (direct fluorescent antibody test / DFAT) in brain tissue of infected animals. This test has been used for more than 40 years and used as a standard in the diagnosis of rabies. The principle is that the bond between rabies antigen and specific antibodies that have been labeled with a fluorescent compound that will glow making it easier detection. However, the drawback is the test subject must be injected prior to death (euthanasia) can therefore not be used on humans. However, similar tests can still be done using serum, spinal fluid, or saliva of patients while not giving 100% accuracy. In addition, the diagnosis can also be done with the neck skin biopsy or corneal epithelial cells, although the results are not very precise so that will be done again after the post mortem diagnosis of infected animals or humans died.